I know the route very well.
The shortest route is to cross direct from Holland to anywhere off of the South Coast of England then follow the coast along to Southampton.
This isn't nessesary the easiest way!!!
Depending on the weather I have found it better to follow the French coast along until you can just about make out England which is around Dungeness, then cross and follow the coast to Southampton.
Unfortunatly I cannot make it but have fun
PS it is about 200 miles and you can get petrol in Nuiewport,Eastbourne, Brighton, Hayling Island and Southampton on the quayside