As far as I know, there's no advantage to one over the other aside from connector size. Both use the same 5-wire cable, and they're just connectors, so they do the same thing. You could argue that the reduced size means less sealing area for leaks, but I don't really buy that for something that's not often disconnected and reconnected.
I think the deciding factor should be what you've already got. If your system is currently blue, go with blue. If it's red, go red.
If it's a new installation, I'd tend towards red as it is newer and more likely to become "standard", but that's about the only reason, unless you are really tight on space whereever the connectors end up falling.