In a word - Yes!
I was doing that following a rebore / piston replacement last summmer. Also don't go too near an EPA boat - they might take offence to the oil slick...
When you are finished the 10 hrs, take the plugs out & give them a good clean. Probably also worth giving the prop a clean too so you don't get manky later.
burning off what's lurking in the exhaust shouldn't take too long after that!